17α-Hydroxyprogesterone CAS 68-96-2

Ro-ràdh 17 α- Tha hydroxyprogesterone, ris an canar uaireannan Hydroxyprogesterone (Beurla: hydroxyprogesterone, OHP), na steroid progesterone endogenous coltach ri progesterone, agus tha e cuideachd na ro-ruithear biosynthesis de mhòran hormona steroid endogenous, a’ toirt a-steach androgen, estrogen, glucocorticoid agus mineralocorticoid. cuid de neurosteroids.Tha bioactive 17-Hydroxyprogesterone (17-OHP) na progesterone endogenous agus eadar-mheadhanach ceimigeach ann am biosynthesis de hormonaichean steroid eile.Sgrùdaidhean in vitro 17 α- Tha OHP na neach-gabhail receptor chemobookin coltach ri progesterone, ged a tha a bhuaidh gu math lag.Tha e cuideachd na eadar-mheadhanach ceimigeach ann am biosynthesis de hormonaichean steroid leithid androgens, estrogen, hormonaichean gnè, glucocorticoids, agus mineralocorticoids.Sgrùdadh In vivo 17 Tha hydroxyprogesterone na inneal steroid èifeachdach airson GVBD (briseadh bileagan gintinn).Criostalachadh feartan ceimigeach (acetone/hexane).Puing leaghaidh 221 ℃ (219-220 ℃).[α] 20/D+97 ° (clorofor